Francesco Arena

The Arena: December 1966: Arena

The Arena: December 1965: Arena

Francesco Boato

Francesco Blast

Hog thyroid tautomerase (EC 5.3.2.1, phenylpyruvate keto-enol isomerase), an enzyme which is believed to play a role in the biosynthesis of thyroxine, has been purified over lOOO-fold. The purification procedure involves a heat step at 70”, gel f&ration on Sephadex G-100, ion exchange chromatography on carboxymethyl Sephadex C-50, and, finally, gel titration on Sephadex G-50. The enzyme is homo...

De Francesco 8 pages

Hepatitis C virus (HCV) will continue to be a serious global health threat for many years to come because of the chronic nature of the infection, its high prevalence and the significant morbidity of the resulting disease. Recently, a small number of molecules have produced encouraging results in proof-of-concept clinical trials. At the same time, preclinical evidence is accumulating that develo...